Cogent Biosciences Inc

Cogent Biosciences Inc (COGT) Stock Analysis

$29.510

+1.425 (+4.83%)At close

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High
29.780
Open
28.330
VWAP
29.21
Volume
3.04M
Mkt Cap
922.86M
Low
28.330
Amount
88.78M
EV/EBITDA, TTM
0.00

Cogent Biosciences, Inc. is a clinical-stage biotechnology company. It is focused on developing precision therapies for genetically defined diseases. Its approach is to design rational precision therapies that treat the underlying cause of disease and improve the lives of patients. Its advanced program is bezuclastinib, also known as CGT9486, a highly selective tyrosine kinase inhibitor that is designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. KIT D816V is responsible for driving systemic mastocytosis (SM), a serious and rare disease caused by unchecked proliferation of mast cells. The Company has on-going Phase I studies of its CNS-penetrant, selective mutant ErbB2 inhibitor and its potential best-in-class, wild-type-sparing, PI3Ka inhibitor. In addition, the Company’s research team is developing a portfolio of novel targeted therapies to help patients fighting serious, genetically driven diseases targeting mutations in KRAS and JAK2.

AI analysis of Cogent Biosciences Inc (COGT)

Buy

Cogent Biosciences Inc is a good buy right now, trading at $31 with a strong upside potential. Analysts have set a price target of $62, indicating a potential upside of 100% from the current price. Additionally, the company has recently submitted a New Drug Application for Bezuclastinib, which could significantly boost its market position. However, the main risk is the negative earnings trend, with an EPS of -0.52 reported in the last quarter.

Analyst Ratings (3)

+70.65% upside
Buy
3 Buy
0 Hold
0 Sell
Current: 29.51
Low
34.00
Average
50.36
High
67.00

JPMorgan

2026-09-09

Price Target

$62

Overweight

Guggenheim

2026-08-12

Price Target

$52

Buy

H.C. Wainwright

2026-05-06

Price Target

$55

Buy

Jefferies

2026-03-16

Price Target

$55

Buy

Baird

2026-02-19

Price Target

$35

Neutral

Valuation Metrics

The current forward P/E ratio for Cogent Biosciences Inc (COGT) is 0.00, compared to its 5-year average forward P/E of -4.78.

Forward P/E

Overvalued
5Y Average P/E
-4.78
Current P/E
0.00
Overvalued
-1.75
Undervalued
-7.81

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-2.78
Current EV/EBITDA
0.00
Overvalued
1.12
Undervalued
-6.67

Forward P/S

Fair
5Y Average P/S
32556.81
Current P/S
17.22
Overvalued
225921.55
Undervalued
-160807.94

Alphio AI Price Scenarios for COGT

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%COGT

$13.42

Scenario price

B

Base

Base · 50%COGT

$11.72

Scenario price

B

Bear

Bear · 25%COGT

$10.02

Scenario price

Whales holding COGT

S

Sofinnova Investments, Inc.

+ HoldingCOGT

+9.67%

3M Return

J

J. Goldman & Co., L.P.

+ HoldingCOGT

+2.97%

3M Return

B

Burkehill Global Management, LP

+ HoldingCOGT

-2.26%

3M Return

D

Deerfield Management Company, L.P.

+ HoldingCOGT

-6.90%

3M Return

B

Boothbay Fund Management, LLC

+ HoldingCOGT

-7.72%

3M Return

R

RTW Investments, LP

+ HoldingCOGT

-8.29%

3M Return

Events Timeline

2026-09-15 (ET)

08:30:00

Cogent Biosciences' New Drug Application Accepted by FDA, Target Date June 29, 2027

2026-08-19 (ET)

13:00:00

H.C. Wainwright Gives Cogent Buy Rating

2026-06-30 (ET)

08:30:00

Cogent Biosciences Submits NDA for Bezuclastinib

2026-05-31 (ET)

16:40:00

Cogent Biosciences Announces GIST Clinical Trial Data

2026-05-28 (ET)

08:10:00

Cogent Biosciences' NDA for Bezuclastinib Accepted by FDA for Priority Review

News

COGT FAQ — answered by Alphio AI

Cogent Biosciences, Inc. is a clinical-stage biotechnology company. It is focused on developing precision therapies for genetically defined diseases. Its approach is to design rational precision therapies that treat the underlying cause of disease and improve the lives of patients. Its advanced program is bezuclastinib, also known as CGT9486, a highly selective tyrosine kinase inhibitor that is designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. KIT D816V is responsible for driving systemic mastocytosis (SM), a serious and rare disease caused by unchecked proliferation of mast cells. The Company has on-going Phase I studies of its CNS-penetrant, selective mutant ErbB2 inhibitor and its potential best-in-class, wild-type-sparing, PI3Ka inhibitor. In addition, the Company’s research team is developing a portfolio of novel targeted therapies to help patients fighting serious, genetically driven diseases targeting mutations in KRAS and JAK2. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Cogent Biosciences Inc is a good buy right now, trading at $31 with a strong upside potential. Analysts have set a price target of $62, indicating a potential upside of 100% from the current price. Additionally, the company has recently submitted a New Drug Application for Bezuclastinib, which could significantly boost its market position. However, the main risk is the negative earnings trend, with an EPS of -0.52 reported in the last quarter.

3 analysts cover COGT: 3 rate it Buy, 0 Hold and 0 Sell. The average price target is 50.36.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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