Celldex Therapeutics Inc

Celldex Therapeutics Inc (CLDX) Stock Analysis

$27.530

-1.332 (-4.84%)At close

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High
28.890
Open
28.890
VWAP
27.96
Volume
997.97K
Mkt Cap
2.48B
Low
27.465
Amount
27.90M
EV/EBITDA, TTM
-0.06

Celldex Therapeutics, Inc. is a clinical-stage biotechnology company. The Company is focused on exploring the science of mast cell biology and the development of transformative therapeutics for patients. Its pipeline includes antibody-based therapeutics which have the ability to engage the human immune system and/or directly affect critical pathways to improve the lives of patients with severe inflammatory, allergic, autoimmune and other devastating diseases. Its drug candidates include monoclonal and bispecific antibodies designed to address mast cell mediated diseases. Its Barzolvolimab (CDX-0159) is a monoclonal antibody that specifically binds the KIT receptor and potently inhibits its activity, which is being studied across multiple mast cell driven diseases, including Chronic Urticarias, Prurigo Nodularis, Atopic Dermatitis and Eosinophilic Esophagitis. The Company’s bispecific platform includes CDX- 622. The CDX- 622 is a bispecific candidate for inflammatory diseases.

celldex.com

AI analysis of Celldex Therapeutics Inc (CLDX)

Hold

Celldex Therapeutics Inc is currently not a strong buy due to its low RSI of 27.687, indicating oversold conditions, and a significant 28.01% decline over the last 20 days. However, the positive news regarding the efficacy of Barzolvolimab and raised price targets from analysts suggest potential upside. The main risk is the ongoing investigation into the company's directors, which could impact shareholder confidence.

Analyst Ratings (7)

+99.78% upside
Buy
4 Buy
3 Hold
0 Sell
Current: 27.53
Low
24.00
Average
55.00
High
90.00

H.C. Wainwright

2026-10-02

Price Target

$64

Buy

Leerink

2026-09-23

Price Target

$88

Outperform

Morgan Stanley

2026-09-23

Price Target

$57

Overweight

H.C. Wainwright

2026-09-22

Price Target

$64

Buy

Morgan Stanley

2026-08-07

Price Target

$46

Overweight

Valuation Metrics

The current forward P/E ratio for Celldex Therapeutics Inc (CLDX) is 0.00, compared to its 5-year average forward P/E of -11.85.

Forward P/E

Strongly Overvalued
5Y Average P/E
-11.85
Current P/E
0.00
Overvalued
-7.18
Undervalued
-16.51

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-2.45
Current EV/EBITDA
-0.06
Overvalued
1.17
Undervalued
-6.07

Forward P/S

Undervalued
5Y Average P/S
531.98
Current P/S
228.22
Overvalued
823.67
Undervalued
240.29

Alphio AI Price Scenarios for CLDX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%CLDX

$42.51

Scenario price

B

Base

Base · 50%CLDX

$32.69

Scenario price

B

Bear

Bear · 25%CLDX

$17.09

Scenario price

Whales holding CLDX

B

Bellevue Asset Management AG

+ HoldingCLDX

-1.47%

3M Return

R

Rock Springs Capital Management LP

+ HoldingCLDX

-12.27%

3M Return

A

ADAR1 Capital Management, LLC

+ HoldingCLDX

-16.51%

3M Return

N

Novo Holdings A/S

+ HoldingCLDX

-21.75%

3M Return

Events Timeline

2026-09-22 (ET)

16:30:00

Dow Falls, Nasdaq Rises as Oil Prices Ease Slightly

12:30:00

Celldex Shares Drop 11.4% to $33.58

12:00:00

Dow Falls Nearly 300 Points, Nasdaq Rises Nearly 100 Points

10:30:00

Celldex Shares Down 5.1% to $35.97

07:30:00

Celldex Reports Positive Results from EMBARQ-CSU1 and CSU2 Trials

News

CLDX FAQ — answered by Alphio AI

Celldex Therapeutics, Inc. is a clinical-stage biotechnology company. The Company is focused on exploring the science of mast cell biology and the development of transformative therapeutics for patients. Its pipeline includes antibody-based therapeutics which have the ability to engage the human immune system and/or directly affect critical pathways to improve the lives of patients with severe inflammatory, allergic, autoimmune and other devastating diseases. Its drug candidates include monoclonal and bispecific antibodies designed to address mast cell mediated diseases. Its Barzolvolimab (CDX-0159) is a monoclonal antibody that specifically binds the KIT receptor and potently inhibits its activity, which is being studied across multiple mast cell driven diseases, including Chronic Urticarias, Prurigo Nodularis, Atopic Dermatitis and Eosinophilic Esophagitis. The Company’s bispecific platform includes CDX- 622. The CDX- 622 is a bispecific candidate for inflammatory diseases. It operates in the Healthcare sector (IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES industry).

Celldex Therapeutics Inc is currently not a strong buy due to its low RSI of 27.687, indicating oversold conditions, and a significant 28.01% decline over the last 20 days. However, the positive news regarding the efficacy of Barzolvolimab and raised price targets from analysts suggest potential upside. The main risk is the ongoing investigation into the company's directors, which could impact shareholder confidence.

7 analysts cover CLDX: 4 rate it Buy, 3 Hold and 0 Sell. The average price target is 55.00.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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