aTyr Pharma Inc

aTyr Pharma Inc (ATYR) Stock Analysis

$5.370

+0.245 (+4.56%)At close

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High
5.600
Open
4.830
VWAP
5.26
Volume
229.67K
Mkt Cap
—
Low
4.810
Amount
1.21M
EV/EBITDA, TTM
0.00

aTyr Pharma, Inc. is a clinical-stage biotechnology company. The Company is leveraging evolutionary intelligence to translate tRNA synthetase biology into new therapies for fibrosis and inflammation. Its lead therapeutic candidate is efzofitimod, a first-in-class biologic immunomodulator in clinical development for the treatment of interstitial lung disease (ILD), a group of immune-mediated disorders that can cause inflammation and fibrosis, or scarring, of the lungs. Efzofitimod is a tRNA synthetase-derived therapy that selectively modulates activated myeloid cells through neuropilin-2 (NRP2) to resolve aberrant inflammation without immune suppression and potentially prevent the progression of fibrosis. ATYR0101 is a fusion protein derived from a domain of aspartyl-tRNA synthetase (DARS). ATYR0750 is a fusion protein derived from the domain of alanyl-tRNA synthetase (AARS). ATYR0750 is a novel ligand to fibroblast growth factor receptor 4 (FGFR4).

AI analysis of aTyr Pharma Inc (ATYR)

Sell

Currently, aTyr Pharma Inc is not a good buy. The stock is trading at $0.1651, which is significantly lower than its analyst price target of $3.50, indicating potential upside. However, the stock has seen a year-to-date change of -78.25% and a 1-year change of -83.04%, reflecting a severe downtrend. Additionally, the RSI is at 5.767, indicating that the stock is extremely oversold, but this could also suggest a lack of buying interest. The main risk is the company's ongoing financial losses, with a net income of -$10.31 million reported in Q2 2026, which raises concerns about its sustainability and ability to recover.

Valuation Metrics

The current forward P/E ratio for aTyr Pharma Inc (ATYR) is 0.00, compared to its 5-year average forward P/E of -2.79.

Forward P/E

Overvalued
5Y Average P/E
-2.79
Current P/E
0.00
Overvalued
-1.06
Undervalued
-4.52

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-1.18
Current EV/EBITDA
0.00
Overvalued
0.65
Undervalued
-3.01

Forward P/S

Fair
5Y Average P/S
521.41
Current P/S
0.00
Overvalued
1568.94
Undervalued
-526.12

Events Timeline

2026-10-19 (ET)

07:30:00

aTyr Pharma Collaborates with Albert Einstein College on ATYR2810 Development

2026-10-13 (ET)

08:30:00

aTyr Pharma Publishes Study on Anti-Fibrotic Effects of ATYR0101

2026-09-24 (ET)

06:30:00

aTyr Pharma Aligns with FDA to Advance Phase 3 Study of efzofitimod

2026-08-07 (ET)

16:30:00

Company Cash Reserves Reach $58.9 Million, Expected to Sustain Operations Until Late 2028

16:30:00

aTyr Pharma Announces Q2 2026 Results and Restructuring

News

ATYR FAQ — answered by Alphio AI

aTyr Pharma, Inc. is a clinical-stage biotechnology company. The Company is leveraging evolutionary intelligence to translate tRNA synthetase biology into new therapies for fibrosis and inflammation. Its lead therapeutic candidate is efzofitimod, a first-in-class biologic immunomodulator in clinical development for the treatment of interstitial lung disease (ILD), a group of immune-mediated disorders that can cause inflammation and fibrosis, or scarring, of the lungs. Efzofitimod is a tRNA synthetase-derived therapy that selectively modulates activated myeloid cells through neuropilin-2 (NRP2) to resolve aberrant inflammation without immune suppression and potentially prevent the progression of fibrosis. ATYR0101 is a fusion protein derived from a domain of aspartyl-tRNA synthetase (DARS). ATYR0750 is a fusion protein derived from the domain of alanyl-tRNA synthetase (AARS). ATYR0750 is a novel ligand to fibroblast growth factor receptor 4 (FGFR4). It operates in the Healthcare sector (BIOLOGICAL PRODUCTS, EXCEPT DIAGNOSTIC SUBSTANCES industry).

Currently, aTyr Pharma Inc is not a good buy. The stock is trading at $0.1651, which is significantly lower than its analyst price target of $3.50, indicating potential upside. However, the stock has seen a year-to-date change of -78.25% and a 1-year change of -83.04%, reflecting a severe downtrend. Additionally, the RSI is at 5.767, indicating that the stock is extremely oversold, but this could also suggest a lack of buying interest. The main risk is the company's ongoing financial losses, with a net income of -$10.31 million reported in Q2 2026, which raises concerns about its sustainability and ability to recover.

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