Arrowhead Pharmaceuticals, Inc.

Arrowhead Pharmaceuticals, Inc. (ARWR) Stock Analysis

$55.900

-2.482 (-4.44%)At close

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High
58.450
Open
58.450
VWAP
56.73
Volume
1.77M
Mkt Cap
3.19B
Low
55.830
Amount
100.61M
EV/EBITDA, TTM
-12.67

Arrowhead Pharmaceuticals, Inc. develops medicines that treat intractable diseases by silencing the genes that cause them. The Company's therapies, using a broad portfolio of ribonucleic acid (RNA) chemistries and modes of delivery, trigger the RNA interference (RNAi) mechanism to induce rapid, deep and durable knockdown of target genes. Its Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. It is focused on various therapeutic areas, such as cardiometabolic, pulmonary, liver, neuromuscular and others. It has over 18 discovered drug candidates in clinical trials ranging from early stage (Phase I) to late stage (Phase III). The Company's pipeline products include plozasiran, zodasiran, olpasiran, ARO-RAGE, SRP-1002, GSK4532990, fazirsiran, daplusiran/tomligisiran, ARO-CFB, ARO-INHBE, ARO-C3, ARO-PNPLA3, SRP-1001 (ARO-DUX4), SRP-1003 (ARO-DM1), SRP-1004 (ARO-ATXN2), and others.

AI analysis of Arrowhead Pharmaceuticals, Inc. (ARWR)

Hold

Arrowhead Pharmaceuticals Inc is currently a hold. The stock is priced at $55.90, significantly below the analyst price targets of $74 from Goldman Sachs and $108 from Citi, indicating potential upside. However, the RSI is at a very low 17.125, suggesting the stock is oversold, which could lead to a rebound. The company has shown promising early trial results for its Alzheimer's drug, ARO-MAPT, with a 73% reduction in tau protein levels, which could drive future growth. However, the risk remains high as the stock has a forward P/E of 111.11 and has seen a 10.92% decline over the past five days, indicating volatility and uncertainty in the market.

Valuation Metrics

The current forward P/E ratio for Arrowhead Pharmaceuticals, Inc. (ARWR) is 111.11, compared to its 5-year average forward P/E of 5.32.

Forward P/E

Strongly Overvalued
5Y Average P/E
5.32
Current P/E
111.11
Overvalued
52.61
Undervalued
-41.97

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-10.58
Current EV/EBITDA
-12.67
Overvalued
22.20
Undervalued
-43.36

Forward P/S

Fair
5Y Average P/S
21.72
Current P/S
25.18
Overvalued
31.74
Undervalued
11.69

Alphio AI Price Scenarios for ARWR

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%ARWR

$20.14

Scenario price

B

Base

Base · 50%ARWR

$18.75

Scenario price

B

Bear

Bear · 25%ARWR

$14.63

Scenario price

Whales holding ARWR

W

Wanjia Asset Management Co., Ltd.

+ HoldingARWR

+11.08%

3M Return

S

Summit Partners Public Asset Management, LLC

+ HoldingARWR

-7.12%

3M Return

K

Keystone Investors Pte. Ltd.

+ HoldingARWR

-8.35%

3M Return

D

Deerfield Management Company, L.P.

+ HoldingARWR

-8.64%

3M Return

I

Integral Health Asset Management, LLC

+ HoldingARWR

-8.91%

3M Return

V

Vestal Point Capital, LP

+ HoldingARWR

-15.07%

3M Return

Events Timeline

2026-10-14 (ET)

08:00:00

Arrowhead Pharmaceuticals Announces Interim Results of ARO-MAPT Clinical Trial

2026-10-07 (ET)

08:00:00

Arrowhead Pharmaceuticals' plozasiran Enters FDA STAR Program

2026-09-15 (ET)

08:00:00

Arrowhead Pharmaceuticals Announces Interim Data for ARO-DIMER-PA Clinical Trial

2026-08-30 (ET)

16:30:00

Arrowhead Pharmaceuticals Reports Plozasiran Study Results, 79% Reduction in Triglycerides in Three Months

2026-07-27 (ET)

08:00:00

Arrowhead Completes Enrollment in YOSEMITE Trial for Zodasiran

News

ARWR FAQ — answered by Alphio AI

Arrowhead Pharmaceuticals, Inc. develops medicines that treat intractable diseases by silencing the genes that cause them. The Company's therapies, using a broad portfolio of ribonucleic acid (RNA) chemistries and modes of delivery, trigger the RNA interference (RNAi) mechanism to induce rapid, deep and durable knockdown of target genes. Its Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. It is focused on various therapeutic areas, such as cardiometabolic, pulmonary, liver, neuromuscular and others. It has over 18 discovered drug candidates in clinical trials ranging from early stage (Phase I) to late stage (Phase III). The Company's pipeline products include plozasiran, zodasiran, olpasiran, ARO-RAGE, SRP-1002, GSK4532990, fazirsiran, daplusiran/tomligisiran, ARO-CFB, ARO-INHBE, ARO-C3, ARO-PNPLA3, SRP-1001 (ARO-DUX4), SRP-1003 (ARO-DM1), SRP-1004 (ARO-ATXN2), and others. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Arrowhead Pharmaceuticals Inc is currently a hold. The stock is priced at $55.90, significantly below the analyst price targets of $74 from Goldman Sachs and $108 from Citi, indicating potential upside. However, the RSI is at a very low 17.125, suggesting the stock is oversold, which could lead to a rebound. The company has shown promising early trial results for its Alzheimer's drug, ARO-MAPT, with a 73% reduction in tau protein levels, which could drive future growth. However, the risk remains high as the stock has a forward P/E of 111.11 and has seen a 10.92% decline over the past five days, indicating volatility and uncertainty in the market.

Community

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DarkRelay3 days ago

$ARWR "I do believe that delivering oligonucleotides via subcutaneous administration to the brain is a therapeutic Holy Grail." Chris Anzalone CEO

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