Annexon, Inc.

Annexon, Inc. (ANNX) Stock Analysis

$4.970

-0.265 (-5.33%)At close

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High
5.205
Open
5.180
VWAP
5.04
Vol
1.62M
Mkt Cap
508.10M
Low
4.945
Amount
8.16M
EV/EBITDA, TTM
0.00

Annexon, Inc. is a clinical-stage biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. It identifies and characterizes the role of the classical complement pathway in three therapeutic areas: autoimmune, neurodegeneration and ophthalmology, using its proprietary platform. Its lead candidate, ANX005, an investigational, full-length monoclonal antibody (mAb), is formulated for intravenous administration as the potential first targeted treatment for patients with Guillain-Barre Syndrome (GBS). It is advancing ANX1502, a novel small-molecule inhibitor of classical complement designed for oral administration in a range of chronic autoimmune diseases. It is also advancing ANX007, designed to block C1q locally in the eye, to provide complete protection against excess classical complement activity and the loss of photoreceptor neurons.

AI analysis of Annexon, Inc. (ANNX)

buy

Annexon Inc (ANNX) is a good buy right now due to its current price of $4.97, which is significantly lower than the analyst price target of $25 from Needham, indicating a potential upside of over 400%. Additionally, the stock has shown a remarkable 140.10% increase over the past year, suggesting strong long-term growth potential. However, the main risk is the ongoing net losses, which reached $55.3 million in Q2 2026, reflecting a challenging financial environment.

Valuation Metrics

The current forward P/E ratio for Annexon, Inc. (ANNX) is 0.00, compared to its 5-year average forward P/E of -2.97.

Forward P/E

Overvalued
5Y Average P/E
-2.97
Current P/E
0.00
Overvalued
-1.22
Undervalued
-4.71

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-0.80
Current EV/EBITDA
0.00
Overvalued
0.24
Undervalued
-1.83

Forward P/S

Fair
5Y Average P/S
19.53
Current P/S
25.41
Overvalued
96.92
Undervalued
-57.86

Alphio AI Price Scenarios for ANNX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%ANNX

$3.01

Scenario price

B

Base

Base · 50%ANNX

$2.80

Scenario price

B

Bear

Bear · 25%ANNX

$2.50

Scenario price

Whales holding ANNX

L

Logos Global Management, L.P.

+ HoldingANNX

+17.53%

3M Return

B

Bain Capital Life Sciences Investors, LLC

+ HoldingANNX

+14.97%

3M Return

B

BVF Partners L.P.

+ HoldingANNX

+11.78%

3M Return

B

Bellevue Asset Management AG

+ HoldingANNX

+9.20%

3M Return

A

Artal Group S.A.

+ HoldingANNX

-0.61%

3M Return

Events Timeline

2026-08-12 (ET)

06:30:00

Annexon Cash and Short-term Investments Reach $209.2 Million

06:30:00

Annexon Adds Month 24 Dual Primary Endpoint in ARCHER II Trial

2026-08-06 (ET)

10:00:00

Annexon Reports Tanruprubart Efficacy in Guillain-Barre Syndrome Patients

2026-05-07 (ET)

16:10:00

Annexon Anticipates Key Data from ARCHER II Trial

2026-03-31 (ET)

13:10:00

Biogen to Acquire Apellis Pharmaceuticals for $41 per Share

News

ANNX FAQ — answered by Alphio AI

Annexon, Inc. is a clinical-stage biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. It identifies and characterizes the role of the classical complement pathway in three therapeutic areas: autoimmune, neurodegeneration and ophthalmology, using its proprietary platform. Its lead candidate, ANX005, an investigational, full-length monoclonal antibody (mAb), is formulated for intravenous administration as the potential first targeted treatment for patients with Guillain-Barre Syndrome (GBS). It is advancing ANX1502, a novel small-molecule inhibitor of classical complement designed for oral administration in a range of chronic autoimmune diseases. It is also advancing ANX007, designed to block C1q locally in the eye, to provide complete protection against excess classical complement activity and the loss of photoreceptor neurons. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Annexon Inc (ANNX) is a good buy right now due to its current price of $4.97, which is significantly lower than the analyst price target of $25 from Needham, indicating a potential upside of over 400%. Additionally, the stock has shown a remarkable 140.10% increase over the past year, suggesting strong long-term growth potential. However, the main risk is the ongoing net losses, which reached $55.3 million in Q2 2026, reflecting a challenging financial environment.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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