Syndax Pharmaceuticals Inc

Syndax Pharmaceuticals Inc (SNDX) Stock Analysis

$19.540

-0.602 (-3.08%)At close

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High
20.045
Open
19.980
VWAP
19.68
Vol
1.04M
Mkt Cap
1.73B
Low
19.470
Amount
20.52M
EV/EBITDA, TTM
-8.06

Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.

syndax.com

AI analysis of Syndax Pharmaceuticals Inc (SNDX)

hold

Syndax Pharmaceuticals Inc (SNDX) is currently trading at $19.54, which is below its recent analyst price targets, suggesting potential upside. However, the stock has an RSI of 40.40, indicating it is nearing oversold territory, but still not a strong buy signal. The company reported a Q2 EPS of -0.55, missing expectations by $0.09, which raises concerns about profitability. Additionally, the forward P/E ratio is currently at 0, reflecting uncertainty in future earnings. The main risk is the significant net loss of $49.36 million reported in Q2 2026, which could affect investor confidence and future financing capabilities.

Analyst Ratings (8)

+100.15% upside
Buy
8 Buy
0 Hold
0 Sell
Current: 19.54
Low
27.00
Average
39.11
High
56.00

UBS

2026-08-21

Price Target

$33

Buy

JPMorgan

2026-08-11

Price Target

$40

Overweight

H.C. Wainwright

2026-08-05

Price Target

$38

Buy

Guggenheim

2026-06-12

Price Target

$31

Buy

UBS

2026-05-13

Price Target

$37

Buy

Valuation Metrics

The current forward P/E ratio for Syndax Pharmaceuticals Inc (SNDX) is 0.00, compared to its 5-year average forward P/E of -6.60.

Forward P/E

Strongly Overvalued
5Y Average P/E
-6.60
Current P/E
0.00
Overvalued
-4.14
Undervalued
-9.07

Forward EV/EBITDA

Undervalued
5Y Average EV/EBITDA
-4.75
Current EV/EBITDA
-8.06
Overvalued
-2.97
Undervalued
-6.54

Forward P/S

Fair
5Y Average P/S
302.72
Current P/S
3.89
Overvalued
1020.32
Undervalued
-414.87

Whales holding SNDX

O

OrbiMed Advisors LLC

+ HoldingSNDX

+5.01%

3M Return

S

Soleus Capital Management, L.P.

+ HoldingSNDX

+3.63%

3M Return

Events Timeline

2026-06-11 (ET)

08:30:00

Syndax Releases Revuforj Clinical Trial Data

2026-06-04 (ET)

07:40:00

Syndax Announces $250M Convertible Senior Note Offering Due 2031

2026-04-30 (ET)

16:30:00

Company Reports Q1 Revenue of $64.86M, Below Expectations

2026-02-26 (ET)

16:30:00

Syndax Expects FY26 R&D and SG&A Expenses of Approximately $400M

16:30:00

Syndax Reports Q4 Revenue of $68.73M, Beating Consensus

News

SNDX FAQ — answered by Alphio AI

Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Syndax Pharmaceuticals Inc (SNDX) is currently trading at $19.54, which is below its recent analyst price targets, suggesting potential upside. However, the stock has an RSI of 40.40, indicating it is nearing oversold territory, but still not a strong buy signal. The company reported a Q2 EPS of -0.55, missing expectations by $0.09, which raises concerns about profitability. Additionally, the forward P/E ratio is currently at 0, reflecting uncertainty in future earnings. The main risk is the significant net loss of $49.36 million reported in Q2 2026, which could affect investor confidence and future financing capabilities.

8 analysts cover SNDX: 8 rate it Buy, 0 Hold and 0 Sell. The average price target is 39.11.

Esta página es solo para investigación y no constituye asesoramiento de inversión. Los modelos pueden equivocarse. El rendimiento pasado no garantiza resultados futuros.

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