OrbiMed Advisors LLC
+5.01%
3M Return
$19.540
-0.602 (-3.08%)At close
Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.
Syndax Pharmaceuticals Inc (SNDX) is currently trading at $19.54, which is below its recent analyst price targets, suggesting potential upside. However, the stock has an RSI of 40.40, indicating it is nearing oversold territory, but still not a strong buy signal. The company reported a Q2 EPS of -0.55, missing expectations by $0.09, which raises concerns about profitability. Additionally, the forward P/E ratio is currently at 0, reflecting uncertainty in future earnings. The main risk is the significant net loss of $49.36 million reported in Q2 2026, which could affect investor confidence and future financing capabilities.
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Syndax (SNDX) Q2 2026 Earnings Call Transcript

Syndax Pharmaceuticals Q2 2026 Earnings Call Insights

Syndax Pharmaceuticals Q2 Earnings Miss Expectations

Revumenib Shows Promising Clinical Data in Acute Leukemia

Syndax Pharmaceuticals Issues $250M Convertible Senior Notes
Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).
Syndax Pharmaceuticals Inc (SNDX) is currently trading at $19.54, which is below its recent analyst price targets, suggesting potential upside. However, the stock has an RSI of 40.40, indicating it is nearing oversold territory, but still not a strong buy signal. The company reported a Q2 EPS of -0.55, missing expectations by $0.09, which raises concerns about profitability. Additionally, the forward P/E ratio is currently at 0, reflecting uncertainty in future earnings. The main risk is the significant net loss of $49.36 million reported in Q2 2026, which could affect investor confidence and future financing capabilities.
8 analysts cover SNDX: 8 rate it Buy, 0 Hold and 0 Sell. The average price target is 39.11.
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