Tango Therapeutics Inc

Tango Therapeutics Inc (TNGX) Stock Analysis

$23.340

-1.790 (-7.67%)At close

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High
25.085
Open
24.930
VWAP
23.90
Vol
2.00M
Mkt Cap
912.47M
Low
23.275
Amount
47.78M
EV/EBITDA, TTM
-838.52

Tango Therapeutics, Inc. is a clinical-stage biotechnology company dedicated to discovering novel drug targets and delivering precision medicine for the treatment of cancer. The Company's novel small molecules are designed to be selectively active in cancer cells with specific genetic alterations, killing those cancer cells while sparing normal cells. The Company is focused on clinical development of two methylthioadenosine phosphorylase (MTAP)-deleted selective PRMT5 inhibitors: vopimetostat (TNG462) for non-CNS cancers, both as a monotherapy and in combination with RAS inhibitors, and TNG456, brain-penetrant protein arginine methyltransferase 5 (PRMT5) inhibitor, for CNS cancers, including glioblastoma (GBM). Its TNG260 is a first-in-class Co-repressor of the Repressor Element-1 Silencing Transcription (CoREST) inhibitor, which in preclinical studies reversed the immune evasion effect of STK11 loss-of-function mutations.

AI analysis of Tango Therapeutics Inc (TNGX)

buy

Tango Therapeutics Inc (TNGX) is a good buy right now due to its current price of $23.34, which is significantly lower than the average analyst price target of $42 to $60. The stock has a strong year-to-date change of +161.37% and a one-year change of +250.45%, indicating robust growth. However, the RSI is at 29.234, suggesting that the stock is oversold, which could present a buying opportunity. The main risk is the high short interest of 29.53%, which could lead to increased volatility.

Valuation Metrics

The current forward P/E ratio for Tango Therapeutics Inc (TNGX) is 0.00, compared to its 5-year average forward P/E of -5.35.

Forward P/E

Strongly Overvalued
5Y Average P/E
-5.35
Current P/E
0.00
Overvalued
-2.73
Undervalued
-7.97

Forward EV/EBITDA

Strongly Undervalued
5Y Average EV/EBITDA
-106.07
Current EV/EBITDA
-838.52
Overvalued
178.10
Undervalued
-390.24

Forward P/S

Strongly Overvalued
5Y Average P/S
255.65
Current P/S
1628.66
Overvalued
806.25
Undervalued
-294.95

Alphio AI Price Scenarios for TNGX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%TNGX

$1.71

Scenario price

B

Base

Base · 50%TNGX

$1.55

Scenario price

B

Bear

Bear · 25%TNGX

$1.21

Scenario price

Whales holding TNGX

C

Commodore Capital LP

+ HoldingTNGX

+34.35%

3M Return

R

Rock Springs Capital Management LP

+ HoldingTNGX

+18.51%

3M Return

L

Logos Global Management, L.P.

+ HoldingTNGX

+17.53%

3M Return

I

Integral Health Asset Management, LLC

+ HoldingTNGX

+15.08%

3M Return

P

Perceptive Advisors LLC

+ HoldingTNGX

+4.39%

3M Return

S

Soleus Capital Management, L.P.

+ HoldingTNGX

+3.63%

3M Return

Events Timeline

2026-08-15 (ET)

20:30:00

T1 Energy Short Interest Soars to 35.5%

2026-08-11 (ET)

07:30:00

Tango CEO: Vopimetostat Achieves 92% Response Rate in Pancreatic Cancer

2026-08-06 (ET)

19:00:00

Tango Therapeutics Chairman Barbara Weber Steps Down

2026-07-17 (ET)

12:30:00

Nasdaq Falls Over 1% as Chip Makers Plunge

2026-07-10 (ET)

22:00:00

Ondas Holdings Short Interest Rises to 40%

News

TNGX FAQ — answered by Alphio AI

Tango Therapeutics, Inc. is a clinical-stage biotechnology company dedicated to discovering novel drug targets and delivering precision medicine for the treatment of cancer. The Company's novel small molecules are designed to be selectively active in cancer cells with specific genetic alterations, killing those cancer cells while sparing normal cells. The Company is focused on clinical development of two methylthioadenosine phosphorylase (MTAP)-deleted selective PRMT5 inhibitors: vopimetostat (TNG462) for non-CNS cancers, both as a monotherapy and in combination with RAS inhibitors, and TNG456, brain-penetrant protein arginine methyltransferase 5 (PRMT5) inhibitor, for CNS cancers, including glioblastoma (GBM). Its TNG260 is a first-in-class Co-repressor of the Repressor Element-1 Silencing Transcription (CoREST) inhibitor, which in preclinical studies reversed the immune evasion effect of STK11 loss-of-function mutations. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Tango Therapeutics Inc (TNGX) is a good buy right now due to its current price of $23.34, which is significantly lower than the average analyst price target of $42 to $60. The stock has a strong year-to-date change of +161.37% and a one-year change of +250.45%, indicating robust growth. However, the RSI is at 29.234, suggesting that the stock is oversold, which could present a buying opportunity. The main risk is the high short interest of 29.53%, which could lead to increased volatility.

Diese Seite dient nur der Recherche und ist keine Anlageberatung. Modelle können falsch liegen. Vergangene Wertentwicklung ist kein Indikator für die Zukunft.

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