Vertex Pharmaceuticals Inc

Vertex Pharmaceuticals Inc (VRTX) Stock Analysis

$498.500

+13.659 (+2.74%)At close

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High
502.935
Open
490.450
VWAP
496.32
Volume
2.09M
Mkt Cap
121.93B
Low
487.540
Amount
1.04B
EV/EBITDA, TTM
21.54

Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The Company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. It also has a clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. The Company's pipeline also includes PALSONIFY (paltusotine) and atumelnant. PALSONIFY is the once-daily oral therapy for acromegaly.

www.vrtx.com

AI analysis of Vertex Pharmaceuticals Inc (VRTX)

Buy

Vertex Pharmaceuticals is a good buy right now due to its strong revenue growth and positive analyst ratings. The current price is $510.08, with a forward P/E ratio of 24.0964, indicating potential for future earnings growth. Additionally, the gross margin stands at an impressive 85.33%, showcasing the company's profitability. However, insider selling has increased by 753.33%, which is a risk to consider.

Analyst Ratings (27)

+3.49% upside
Buy
22 Buy
5 Hold
0 Sell
Current: 498.50
Low
414.00
Average
515.88
High
604.00

BofA

2026-10-12

Price Target

$667

Buy

RBC Capital

2026-10-08

Price Target

$576

Outperform

UBS

2026-09-29

Price Target

$615

Buy

UBS

2026-09-28

Price Target

$615

Buy

JPMorgan

2026-09-11

Price Target

$560

Overweight

Valuation Metrics

The current forward P/E ratio for Vertex Pharmaceuticals Inc (VRTX) is 24.10, compared to its 5-year average forward P/E of 187.75.

Forward P/E

Fair
5Y Average P/E
187.75
Current P/E
24.10
Overvalued
781.78
Undervalued
-406.28

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
24.04
Current EV/EBITDA
21.54
Overvalued
47.68
Undervalued
0.40

Forward P/S

Fair
5Y Average P/S
8.83
Current P/S
8.81
Overvalued
10.16
Undervalued
7.51

Alphio AI Price Scenarios for VRTX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%VRTX

$566.33

Scenario price

B

Base

Base · 50%VRTX

$566.01

Scenario price

B

Bear

Bear · 25%VRTX

$516.43

Scenario price

Whales holding VRTX

S

SOCIETE GENERALE INVESTMENT SOLUTIONS (FRANCE)

+ HoldingVRTXCMI

+8.67%

3M Return

A

Assenagon Asset Management S.A.

+ HoldingVRTX

+8.58%

3M Return

C

Carmignac Gestion SA

+ HoldingVRTX

+7.99%

3M Return

O

Osmosis Investment Management UK Limited

+ HoldingVRTX

+7.38%

3M Return

P

Putnam LLC

+ HoldingVRTX

+7.26%

3M Return

J

Jennison Associates LLC

+ HoldingVRTX

+7.14%

3M Return

Events Timeline

2026-10-09 (ET)

13:30:00

Vertex Pharmaceuticals Announces New Data from ALYFTREK Study

2026-09-22 (ET)

10:30:00

Maze Stock Jumps 25% to $27.99 After Vertex Kidney Disease Data

08:30:00

Vertex Pharmaceuticals Reports Positive Phase 2b Results for Inaxaplin

2026-09-15 (ET)

08:00:00

Vertex Pharmaceuticals Partners with Lindsey Vonn to Promote JOURNAVX

2026-09-01 (ET)

09:30:00

Vertex Pharmaceuticals Completes Acquisition of Crinetics for Approximately $10 Billion

News

VRTX FAQ — answered by Alphio AI

Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The Company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. It also has a clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. The Company's pipeline also includes PALSONIFY (paltusotine) and atumelnant. PALSONIFY is the once-daily oral therapy for acromegaly. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Vertex Pharmaceuticals is a good buy right now due to its strong revenue growth and positive analyst ratings. The current price is $510.08, with a forward P/E ratio of 24.0964, indicating potential for future earnings growth. Additionally, the gross margin stands at an impressive 85.33%, showcasing the company's profitability. However, insider selling has increased by 753.33%, which is a risk to consider.

27 analysts cover VRTX: 22 rate it Buy, 5 Hold and 0 Sell. The average price target is 515.88.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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