Syndax Pharmaceuticals Inc

Syndax Pharmaceuticals Inc (SNDX) Stock Analysis

$13.530

-0.407 (-3.01%)At close

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High
14.005
Open
13.920
VWAP
13.64
Volume
3.04M
Mkt Cap
1.73B
Low
13.390
Amount
41.47M
EV/EBITDA, TTM
-5.94

Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.

syndax.com

AI analysis of Syndax Pharmaceuticals Inc (SNDX)

Hold

Syndax Pharmaceuticals Inc is currently priced at $16.99, with a low RSI of 32.301 indicating it may be oversold. However, the company reported a Q2 EPS of -0.55, missing expectations by $0.09, which raises concerns about profitability. The forward P/E ratio is not applicable due to negative earnings, and while the gross margin remains strong at 95.59%, the significant net income loss of -49.36 million in Q2 2026 is a major risk. Given these factors, it is advisable to hold rather than buy at this time.

Analyst Ratings (8)

+189.06% upside
Buy
8 Buy
0 Hold
0 Sell
Current: 13.53
Low
27.00
Average
39.11
High
56.00

UBS

2026-08-21

Price Target

$33

Buy

JPMorgan

2026-08-11

Price Target

$40

Overweight

H.C. Wainwright

2026-08-05

Price Target

$38

Buy

Guggenheim

2026-06-12

Price Target

$31

Buy

UBS

2026-05-13

Price Target

$37

Buy

Valuation Metrics

The current forward P/E ratio for Syndax Pharmaceuticals Inc (SNDX) is 0.00, compared to its 5-year average forward P/E of -6.51.

Forward P/E

Strongly Overvalued
5Y Average P/E
-6.51
Current P/E
0.00
Overvalued
-4.11
Undervalued
-8.91

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-4.78
Current EV/EBITDA
-5.94
Overvalued
-2.97
Undervalued
-6.60

Forward P/S

Fair
5Y Average P/S
302.24
Current P/S
2.71
Overvalued
1020.03
Undervalued
-415.56

Whales holding SNDX

W

Wiener Städtische Wechselseitige Versicherungsverein - Vermögensverwaltung - Vienna Insurance Group

+ HoldingSNDX

+8.38%

3M Return

P

Pale Fire Capital SE

+ HoldingSNDX

-1.78%

3M Return

D

Deerfield Management Company, L.P.

+ HoldingSNDX

-8.23%

3M Return

O

OrbiMed Advisors LLC

+ HoldingSNDX

-14.89%

3M Return

Events Timeline

2026-10-13 (ET)

16:30:00

S&P 500 Earnings Expected to Grow 30% in Q3

12:30:00

S&P 500 Earnings Expected to Grow 30% in Q3

09:00:00

U.S. Stock Futures Mixed as Semiconductor Stocks Plunge

2026-10-12 (ET)

19:30:00

Nasdaq Falls 0.4%, WTI Crude Rises to $93

16:30:00

Syndax Shares Drop 15% to $14 After Idiopathic Pulmonary Fibrosis Miss

News

SNDX FAQ — answered by Alphio AI

Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. It is focused on developing a pipeline of cancer therapies. Its product candidates include Revuforj and Niktimvo. It is developing Revuforj, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant AML. It is also exploring the use of Revuforj as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing Niktimvo, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Syndax Pharmaceuticals Inc is currently priced at $16.99, with a low RSI of 32.301 indicating it may be oversold. However, the company reported a Q2 EPS of -0.55, missing expectations by $0.09, which raises concerns about profitability. The forward P/E ratio is not applicable due to negative earnings, and while the gross margin remains strong at 95.59%, the significant net income loss of -49.36 million in Q2 2026 is a major risk. Given these factors, it is advisable to hold rather than buy at this time.

8 analysts cover SNDX: 8 rate it Buy, 0 Hold and 0 Sell. The average price target is 39.11.

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