Sagimet Biosciences Inc

Sagimet Biosciences Inc (SGMT) Stock Analysis

$10.550

-0.196 (-1.86%)At close

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High
10.810
Open
10.620
VWAP
10.61
Vol
574.00K
Mkt Cap
131.17M
Low
10.470
Amount
6.09M
EV/EBITDA, TTM
0.00

Sagimet Biosciences Inc. is a clinical-stage biopharmaceutical company developing fatty acid synthase (FASN) inhibitors that are designed to target dysfunctional metabolic and fibrotic pathways in diseases resulting from the overproduction of the fatty acid, palmitate. The Company's lead drug candidate, denifanstat, is an oral, once-daily pill and selective FASN inhibitor in development for the treatment of metabolic dysfunction associated steatohepatitis (MASH). Denifanstat has been granted Breakthrough Therapy designation by the FDA for the treatment of non-cirrhotic MASH with moderate to advanced liver fibrosis. The Company is also exploring the use of its FASN inhibitors, which include denifanstat and its pipeline product candidate, TVB-3567, in acne and in select forms of cancer. Denifanstat is being tested in China by its license partner, Ascletis BioScience Co. Ltd., for moderate to severe acne vulgaris and recurrent glioblastoma multiforme in combination with bevacizumab.

sagimet.com

AI analysis of Sagimet Biosciences Inc (SGMT)

buy

Sagimet Biosciences Inc is a good buy right now due to its current price of $10.55, which is significantly below the analyst price target of $56 from Canaccord. The company has a strong cash position of $257.6 million, sufficient to fund operations through 2028, which supports its ongoing clinical trials. However, the main risk is the negative earnings per share (EPS) of -0.26 reported for Q2 2026, indicating ongoing financial losses.

Valuation Metrics

The current forward P/E ratio for Sagimet Biosciences Inc (SGMT) is 0.00, compared to its 5-year average forward P/E of -2.64.

Forward P/E

Overvalued
5Y Average P/E
-2.64
Current P/E
0.00
Overvalued
-1.07
Undervalued
-4.22

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-0.21
Current EV/EBITDA
0.00
Overvalued
0.48
Undervalued
-0.90

Forward P/S

Fair
5Y Average P/S
25.29
Current P/S
84.00
Overvalued
218.93
Undervalued
-168.36

Alphio AI Price Scenarios for SGMT

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%SGMT

$12.11

Scenario price

B

Base

Base · 50%SGMT

$10.31

Scenario price

B

Bear

Bear · 25%SGMT

$9.98

Scenario price

Whales holding SGMT

S

Sofinnova Investments, Inc.

+ HoldingSGMT

+15.48%

3M Return

A

Affinity Asset Advisors, LLC

+ HoldingSGMT

+14.65%

3M Return

B

BVF Partners L.P.

+ HoldingSGMT

+11.78%

3M Return

C

Caligan Partners, LP

+ HoldingSGMT

-6.01%

3M Return

Events Timeline

2026-08-25 (ET)

08:00:00

Sagimet Biosciences AURORA Trial to Start Enrollment in Q4

2026-08-11 (ET)

08:00:00

Sagimet CEO Announces Denifanstat to Enter Phase 3 Clinical Trial in 2026

2026-05-12 (ET)

07:40:00

Sagimet Plans to Initiate Phase 3 Acne Trial in H2 2026

2026-04-20 (ET)

07:10:00

Sagimet Biosciences Appoints Andreas Grauer as Chief Medical Officer

2026-03-11 (ET)

07:40:00

Sagimet CEO: Advancements in MASH and Acne Programs in 2025

News

SGMT FAQ — answered by Alphio AI

Sagimet Biosciences Inc. is a clinical-stage biopharmaceutical company developing fatty acid synthase (FASN) inhibitors that are designed to target dysfunctional metabolic and fibrotic pathways in diseases resulting from the overproduction of the fatty acid, palmitate. The Company's lead drug candidate, denifanstat, is an oral, once-daily pill and selective FASN inhibitor in development for the treatment of metabolic dysfunction associated steatohepatitis (MASH). Denifanstat has been granted Breakthrough Therapy designation by the FDA for the treatment of non-cirrhotic MASH with moderate to advanced liver fibrosis. The Company is also exploring the use of its FASN inhibitors, which include denifanstat and its pipeline product candidate, TVB-3567, in acne and in select forms of cancer. Denifanstat is being tested in China by its license partner, Ascletis BioScience Co. Ltd., for moderate to severe acne vulgaris and recurrent glioblastoma multiforme in combination with bevacizumab. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Sagimet Biosciences Inc is a good buy right now due to its current price of $10.55, which is significantly below the analyst price target of $56 from Canaccord. The company has a strong cash position of $257.6 million, sufficient to fund operations through 2028, which supports its ongoing clinical trials. However, the main risk is the negative earnings per share (EPS) of -0.26 reported for Q2 2026, indicating ongoing financial losses.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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