Uniqure NV

Uniqure NV (QURE) Stock Analysis

$20.970

-0.306 (-1.46%)At close

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High
21.750
Open
21.000
VWAP
21.02
Volume
3.33M
Mkt Cap
220.41M
Low
20.330
Amount
70.03M
EV/EBITDA, TTM
-1.35

Uniqure NV is a company based in the Netherlands specialized in gene therapy. It seeks to develop one-time administered treatments with potentially curative results for patients suffering from genetic and other devastating diseases. It develops, both internally and through partnerships, a pipeline of gene therapies. It produces adeno-associated virus based, or AAV-based, gene therapies in its own facilities with a proprietary, commercial-scale, current good manufacturing practices, compliant, manufacturing process. AMT-061, the Company’s lead product candidate for patients with hemophilia B, is going through a dosing phase of a pivotal study. AMT-130, the product candidate for patients with Huntington’s disease is in Phase I/II clinical study.

AI analysis of Uniqure NV (QURE)

Sell

Given the current price of $22.59 and an RSI of 11.267, which indicates the stock is extremely oversold, it may seem like a potential buying opportunity. However, the stock has dropped 63.58% over the past year and recent disappointing clinical trial results have led to a significant loss of investor confidence. The forward P/E ratio is 27.933, suggesting that the stock is overvalued relative to its earnings potential. The main risk is the recent downgrade from Barclays, which lowered its price target from $60 to $28, reflecting increased uncertainty around the company's prospects. Therefore, despite the low price, the overall outlook is negative, and it is advisable to sell rather than buy at this time.

Analyst Ratings (5)

+137.86% upside
Buy
5 Buy
0 Hold
0 Sell
Current: 20.97
Low
33.00
Average
49.88
High
70.00

Barclays

2026-10-05

Price Target

$28

Equal Weight

RBC Capital

2026-10-02

Price Target

$48

Outperform

Goldman Sachs

2026-09-29

Price Target

$31

Neutral

RBC Capital

2026-09-29

Price Target

—

Outperform

Wells Fargo

2026-09-29

Price Target

$75

Overweight

Valuation Metrics

The current forward P/E ratio for Uniqure NV (QURE) is 27.93, compared to its 5-year average forward P/E of -2.23.

Forward P/E

Overvalued
5Y Average P/E
-2.23
Current P/E
27.93
Overvalued
15.20
Undervalued
-19.65

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-4.55
Current EV/EBITDA
-1.35
Overvalued
-0.01
Undervalued
-9.08

Forward P/S

Fair
5Y Average P/S
18.67
Current P/S
15.18
Overvalued
39.66
Undervalued
-2.33

Alphio AI Price Scenarios for QURE

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%QURE

$12.51

Scenario price

B

Base

Base · 50%QURE

$12.25

Scenario price

B

Bear

Bear · 25%QURE

$9.57

Scenario price

Whales holding QURE

M

Maverick Capital, Ltd.

+ HoldingQURE

+6.11%

3M Return

N

Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.

+ HoldingQURE

+1.67%

3M Return

L

Longaeva Partners L.P.

+ HoldingQURE

-0.84%

3M Return

K

Kinetic Partners Management LP

+ HoldingQURE

-5.13%

3M Return

V

Voss Capital, LP

+ HoldingQURE

-8.34%

3M Return

I

Integral Health Asset Management, LLC

+ HoldingQURE

-8.58%

3M Return

Events Timeline

2026-09-29 (ET)

17:00:00

Major Averages Decline as 30-Year Bond Yield Hits Highest Level Since 2002

12:30:00

uniQure Shares Drop 38.4% to $24.10

12:00:00

Major Averages Dip as 30-Year Bond Yield Hits Highest Level Since 2002

10:30:00

uniQure Shares Drop 36.4% to $24.88

09:00:00

Stock Futures Edge Higher as Tech Stocks Stabilize

News

QURE FAQ — answered by Alphio AI

Uniqure NV is a company based in the Netherlands specialized in gene therapy. It seeks to develop one-time administered treatments with potentially curative results for patients suffering from genetic and other devastating diseases. It develops, both internally and through partnerships, a pipeline of gene therapies. It produces adeno-associated virus based, or AAV-based, gene therapies in its own facilities with a proprietary, commercial-scale, current good manufacturing practices, compliant, manufacturing process. AMT-061, the Company’s lead product candidate for patients with hemophilia B, is going through a dosing phase of a pivotal study. AMT-130, the product candidate for patients with Huntington’s disease is in Phase I/II clinical study. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Given the current price of $22.59 and an RSI of 11.267, which indicates the stock is extremely oversold, it may seem like a potential buying opportunity. However, the stock has dropped 63.58% over the past year and recent disappointing clinical trial results have led to a significant loss of investor confidence. The forward P/E ratio is 27.933, suggesting that the stock is overvalued relative to its earnings potential. The main risk is the recent downgrade from Barclays, which lowered its price target from $60 to $28, reflecting increased uncertainty around the company's prospects. Therefore, despite the low price, the overall outlook is negative, and it is advisable to sell rather than buy at this time.

5 analysts cover QURE: 5 rate it Buy, 0 Hold and 0 Sell. The average price target is 49.88.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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