Nektar Therapeutics

Nektar Therapeutics (NKTR) Stock Analysis

$37.720

+0.849 (+2.25%)At close

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High
38.740
Open
37.150
VWAP
37.80
Volume
684.19K
Mkt Cap
209.78M
Low
36.940
Amount
25.86M
EV/EBITDA, TTM
-6.34

Nektar Therapeutics is a clinical-stage biotechnology company. It is focused on developing treatments that address the underlying immunological dysfunction in autoimmune and chronic inflammatory diseases. In oncology, it is focused on developing medicines based on targeting biological pathways that stimulate and sustain the body’s immune response to fight cancer. Its lead product candidate, rezpegaldesleukin (REZPEG, or NKTR-358), is a novel regulatory T cell stimulator being evaluated in two Phase IIb clinical trials, one in atopic dermatitis and one in alopecia areata. Its pipeline also includes a preclinical bivalent tumor necrosis factor receptor type II (TNFR2) antibody and bispecific programs, NKTR-0165 and NKTR-0166, and a modified hematopoietic colony stimulating factor (CSF) protein, NKTR-422. It is also evaluating NKTR-255, an investigational IL-15 receptor agonist designed to boost the immune system's natural ability to fight cancer, in several ongoing clinical trials.

AI analysis of Nektar Therapeutics (NKTR)

Sell

Nektar Therapeutics is not a good buy right now due to significant recent declines and negative sentiment. The stock is currently priced at $41.17, down 40.98% over the last 20 days, and has a very low RSI of 20.072, indicating oversold conditions. Furthermore, hedge funds have increased selling by 1229.84% in the last quarter, reflecting a lack of confidence in the stock's near-term prospects. The main risk is the ongoing litigation that could impact future growth, which adds uncertainty to the investment.

Analyst Ratings (11)

+227.23% upside
Buy
10 Buy
1 Hold
0 Sell
Current: 37.72
Low
102.00
Average
123.43
High
165.00

Leerink

2026-10-12

Price Target

$130

Outperform

UBS

2026-10-12

Price Target

$53

Neutral

Raymond James

2026-10-08

Price Target

—

Market Perform

Citi

2026-10-05

Price Target

$151

Buy

H.C. Wainwright

2026-10-02

Price Target

$185

Buy

Valuation Metrics

The current forward P/E ratio for Nektar Therapeutics (NKTR) is 34.01, compared to its 5-year average forward P/E of 2.98.

Forward P/E

Strongly Overvalued
5Y Average P/E
2.98
Current P/E
34.01
Overvalued
15.48
Undervalued
-9.51

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-5.25
Current EV/EBITDA
-6.34
Overvalued
7.72
Undervalued
-18.23

Forward P/S

Fair
5Y Average P/S
14.57
Current P/S
24.24
Overvalued
33.44
Undervalued
-4.31

Alphio AI Price Scenarios for NKTR

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%NKTR

$0.66

Scenario price

B

Base

Base · 50%NKTR

$0.52

Scenario price

B

Bear

Bear · 25%NKTR

$0.49

Scenario price

Whales holding NKTR

B

Braidwell LP

+ HoldingNKTR

+19.42%

3M Return

S

Sofinnova Investments, Inc.

+ HoldingNKTR

+9.67%

3M Return

S

Seven Grand Managers LLC

+ HoldingNKTR

-0.15%

3M Return

Q

Quinn Opportunity Partners LLC

+ HoldingNKTR

-4.28%

3M Return

A

Armistice Capital LLC

+ HoldingNKTR

-6.13%

3M Return

T

Two Seas Capital LP

+ HoldingNKTR

-8.89%

3M Return

Events Timeline

2026-10-01 (ET)

16:30:00

Major Averages Little Changed as Micron Reports Strong Q4 Earnings

12:30:00

Nektar Shares Down 21.6% to $47.46

12:00:00

Major Averages Decline as Treasury Yields Rise

10:30:00

Nektar Shares Down 19.8% to $48.55

08:00:00

Nektar Therapeutics Presents Long-Term Data on Rezpegaldesleukin

News

NKTR FAQ — answered by Alphio AI

Nektar Therapeutics is a clinical-stage biotechnology company. It is focused on developing treatments that address the underlying immunological dysfunction in autoimmune and chronic inflammatory diseases. In oncology, it is focused on developing medicines based on targeting biological pathways that stimulate and sustain the body’s immune response to fight cancer. Its lead product candidate, rezpegaldesleukin (REZPEG, or NKTR-358), is a novel regulatory T cell stimulator being evaluated in two Phase IIb clinical trials, one in atopic dermatitis and one in alopecia areata. Its pipeline also includes a preclinical bivalent tumor necrosis factor receptor type II (TNFR2) antibody and bispecific programs, NKTR-0165 and NKTR-0166, and a modified hematopoietic colony stimulating factor (CSF) protein, NKTR-422. It is also evaluating NKTR-255, an investigational IL-15 receptor agonist designed to boost the immune system's natural ability to fight cancer, in several ongoing clinical trials. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Nektar Therapeutics is not a good buy right now due to significant recent declines and negative sentiment. The stock is currently priced at $41.17, down 40.98% over the last 20 days, and has a very low RSI of 20.072, indicating oversold conditions. Furthermore, hedge funds have increased selling by 1229.84% in the last quarter, reflecting a lack of confidence in the stock's near-term prospects. The main risk is the ongoing litigation that could impact future growth, which adds uncertainty to the investment.

11 analysts cover NKTR: 10 rate it Buy, 1 Hold and 0 Sell. The average price target is 123.43.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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