Exelixis Inc

Exelixis Inc (EXEL) Stock Analysis

$54.450

-0.800 (-1.47%)At close

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High
55.250
Open
55.140
VWAP
54.61
Vol
1.49M
Mkt Cap
6.56B
Low
54.120
Amount
81.18M
EV/EBITDA, TTM
11.68

Exelixis, Inc. is an oncology company. The Company has produced four marketed pharmaceutical products, two of which are formulations of its flagship molecule, cabozantinib. It is also advancing and evolving its product pipeline portfolio, including its lead investigational asset, zanzalintinib. Cabozantinib is an inhibitor of multiple tyrosine kinases, including MET, AXL, VEGF receptors and RET and has been also approved as CABOMETYX tablets for advanced renal cell carcinoma, for previously treated hepatocellular carcinoma and for previously treated, radioactive iodine-refractory differentiated thyroid cancer, and as COMETRIQ capsules for progressive, metastatic medullary thyroid cancer. The Company's other two products are COTELLIC, an inhibitor of MEK approved as part of multiple combination regimens to treat specific forms of advanced melanoma and MINNEBRO an oral, non-steroidal, selective blocker of the mineralocorticoid receptor approved the treatment of hypertension in Japan.

AI analysis of Exelixis Inc (EXEL)

hold

Exelixis Inc is currently priced at $54.45, which is above the average analyst price target of $52, suggesting that it may not be a strong buy at this moment. Additionally, the company has shown solid revenue growth with a 1-year change of +46.45%, but it recently lowered its revenue guidance for 2026 by $50 million due to slower product ramp-up, which poses a risk. The RSI is at 49.468, indicating a neutral momentum, and the stock has a forward P/E of 17.42, which is relatively high compared to its growth prospects. Therefore, while there are positive catalysts such as potential new product approvals, the recent guidance cut and current price levels suggest holding rather than buying.

Analyst Ratings (10)

-19.03% downside
Buy
6 Buy
4 Hold
0 Sell
Current: 54.45
Low
30.00
Average
44.09
High
52.00

Leerink

2026-08-06

Price Target

$52

Market Perform

Truist

2026-08-06

Price Target

$52

Hold

Stifel

2026-08-06

Price Target

$51

Hold

Morgan Stanley

2026-07-23

Price Target

$53

Equal Weight

Barclays

2026-07-14

Price Target

$49

Equal Weight

Valuation Metrics

The current forward P/E ratio for Exelixis Inc (EXEL) is 17.42, compared to its 5-year average forward P/E of 23.58.

Forward P/E

Fair
5Y Average P/E
23.58
Current P/E
17.42
Overvalued
35.12
Undervalued
12.04

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
13.33
Current EV/EBITDA
11.68
Overvalued
16.93
Undervalued
9.74

Forward P/S

Overvalued
5Y Average P/S
3.84
Current P/S
4.77
Overvalued
4.41
Undervalued
3.27

Alphio AI Price Scenarios for EXEL

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%EXEL

$51.94

Scenario price

B

Base

Base · 50%EXEL

$42.91

Scenario price

B

Bear

Bear · 25%EXEL

$34.88

Scenario price

Whales holding EXEL

L

LSV Asset Management

+ HoldingEXEL

+1.61%

3M Return

C

Capital Impact Advisors, LLC

+ HoldingEXEL

+1.18%

3M Return

E

EULAV Asset Management

+ HoldingEXEL

+0.97%

3M Return

B

Boothbay Fund Management, LLC

+ HoldingEXEL

+0.22%

3M Return

R

Renaissance Technologies Corp.

+ HoldingEXEL

-1.70%

3M Return

C

Caligan Partners, LP

+ HoldingEXEL

-6.01%

3M Return

EXEL FAQ — answered by Alphio AI

Exelixis, Inc. is an oncology company. The Company has produced four marketed pharmaceutical products, two of which are formulations of its flagship molecule, cabozantinib. It is also advancing and evolving its product pipeline portfolio, including its lead investigational asset, zanzalintinib. Cabozantinib is an inhibitor of multiple tyrosine kinases, including MET, AXL, VEGF receptors and RET and has been also approved as CABOMETYX tablets for advanced renal cell carcinoma, for previously treated hepatocellular carcinoma and for previously treated, radioactive iodine-refractory differentiated thyroid cancer, and as COMETRIQ capsules for progressive, metastatic medullary thyroid cancer. The Company's other two products are COTELLIC, an inhibitor of MEK approved as part of multiple combination regimens to treat specific forms of advanced melanoma and MINNEBRO an oral, non-steroidal, selective blocker of the mineralocorticoid receptor approved the treatment of hypertension in Japan. It operates in the Healthcare sector (BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) industry).

Exelixis Inc is currently priced at $54.45, which is above the average analyst price target of $52, suggesting that it may not be a strong buy at this moment. Additionally, the company has shown solid revenue growth with a 1-year change of +46.45%, but it recently lowered its revenue guidance for 2026 by $50 million due to slower product ramp-up, which poses a risk. The RSI is at 49.468, indicating a neutral momentum, and the stock has a forward P/E of 17.42, which is relatively high compared to its growth prospects. Therefore, while there are positive catalysts such as potential new product approvals, the recent guidance cut and current price levels suggest holding rather than buying.

10 analysts cover EXEL: 6 rate it Buy, 4 Hold and 0 Sell. The average price target is 44.09.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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