Castle Biosciences Inc

Castle Biosciences Inc (CSTL) Stock Analysis

$33.800

+0.703 (+2.08%)At close

Loading chart…
High
34.060
Open
33.130
VWAP
33.45
Volume
381.94K
Mkt Cap
584.17M
Low
32.480
Amount
12.77M
EV/EBITDA, TTM
291.44

Castle Biosciences, Inc. is a molecular diagnostics company offering test solutions to aid clinicians in the diagnosis and treatment of dermatologic cancers, Barrett’s esophagus (BE), uveal melanoma (UM), and in the treatment of mental health conditions. The Company offers around six commercially available proprietary multi-analyte assays with algorithmic analysis (MAAA) tests for use in the fields of dermatology, gastroenterology ophthalmology and includes a test to guide systemic treatment decisions in patients with moderate-to-severe AD. It also offers a proprietary pharmacogenomic (PGx) test to guide optimal drug treatment for patients diagnosed with depression, anxiety and other mental health conditions. Its products include DecisionDx-Melanoma, DecisionDx-SCC, MyPath Melanoma, TissueCypher, IDgenetix, and DecisionDx-UM. DecisionDx-SCC is its proprietary gene expression profile (GEP) test for patients with cutaneous squamous cell carcinoma (SCC).

AI analysis of Castle Biosciences Inc (CSTL)

Buy

Castle Biosciences Inc (CSTL) appears to be a good buy at the current price of $34.42. The company recently reported Q2 2026 revenue of $103.5 million, a significant 20% increase year-over-year, and raised its full-year revenue guidance to between $365 million and $375 million. Additionally, the stock has a gross margin of 74.94% in Q2 2026, showcasing strong profitability potential. However, the main risk is its current negative earnings per share (EPS) of -0.07, indicating ongoing losses that investors should monitor closely.

Valuation Metrics

The current forward P/E ratio for Castle Biosciences Inc (CSTL) is 0.00, compared to its 5-year average forward P/E of -12.66.

Forward P/E

Overvalued
5Y Average P/E
-12.66
Current P/E
0.00
Overvalued
-4.45
Undervalued
-20.86

Forward EV/EBITDA

Strongly Overvalued
5Y Average EV/EBITDA
9.51
Current EV/EBITDA
291.44
Overvalued
77.47
Undervalued
-58.46

Forward P/S

Fair
5Y Average P/S
3.41
Current P/S
2.45
Overvalued
5.72
Undervalued
1.11

Alphio AI Price Scenarios for CSTL

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%CSTL

$18.34

Scenario price

B

Base

Base · 50%CSTL

$16.23

Scenario price

B

Bear

Bear · 25%CSTL

$12.86

Scenario price

Whales holding CSTL

R

RTW Investments, LP

+ HoldingCSTL

-8.29%

3M Return

Events Timeline

2026-09-28 (ET)

07:30:00

Castle Biosciences Publishes Study Showing TissueCypher Test Guides Management Decisions

2026-09-15 (ET)

07:30:00

Castle Biosciences Publishes TissueCypher Study Results

2026-09-09 (ET)

17:00:00

Castle Biosciences Publishes Study on High-Risk Skin SCC

2026-06-16 (ET)

07:30:00

Castle Biosciences' TissueCypher Test Orders Exceed 100,000

2026-05-06 (ET)

16:30:00

Castle Biosciences Q1 Revenue $83.7M, Raises 2026 Revenue Guidance to $345M-$355M

News

CSTL FAQ — answered by Alphio AI

Castle Biosciences, Inc. is a molecular diagnostics company offering test solutions to aid clinicians in the diagnosis and treatment of dermatologic cancers, Barrett’s esophagus (BE), uveal melanoma (UM), and in the treatment of mental health conditions. The Company offers around six commercially available proprietary multi-analyte assays with algorithmic analysis (MAAA) tests for use in the fields of dermatology, gastroenterology ophthalmology and includes a test to guide systemic treatment decisions in patients with moderate-to-severe AD. It also offers a proprietary pharmacogenomic (PGx) test to guide optimal drug treatment for patients diagnosed with depression, anxiety and other mental health conditions. Its products include DecisionDx-Melanoma, DecisionDx-SCC, MyPath Melanoma, TissueCypher, IDgenetix, and DecisionDx-UM. DecisionDx-SCC is its proprietary gene expression profile (GEP) test for patients with cutaneous squamous cell carcinoma (SCC). It operates in the Healthcare sector (SERVICES-MEDICAL LABORATORIES industry).

Castle Biosciences Inc (CSTL) appears to be a good buy at the current price of $34.42. The company recently reported Q2 2026 revenue of $103.5 million, a significant 20% increase year-over-year, and raised its full-year revenue guidance to between $365 million and $375 million. Additionally, the stock has a gross margin of 74.94% in Q2 2026, showcasing strong profitability potential. However, the main risk is its current negative earnings per share (EPS) of -0.07, indicating ongoing losses that investors should monitor closely.

Community

More ↗

No posts yet

Sign up or log in to join the discussion

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

Start trading