Crinetics Pharmaceuticals Inc

Crinetics Pharmaceuticals Inc (CRNX) Stock Analysis

$84.840

-0.008 (-0.01%)At close

Loading chart…
High
84.870
Open
84.860
VWAP
84.85
Vol
1.13M
Mkt Cap
3.43B
Low
84.840
Amount
95.70M
EV/EBITDA, TTM
-9.49

Crinetics Pharmaceuticals, Inc. is a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of therapeutics for rare endocrine diseases and endocrine-related tumors. Its lead development candidate, PALSONIFY (paltusotine), is the first investigational once-daily, oral, selective somatostatin receptor type 2 (SST2) nonpeptide agonist that is in clinical development for acromegaly and carcinoid syndrome associated with neuroendocrine tumors. Its second product candidate is Atumelnant, which is in clinical development for congenital adrenal hyperplasia (CAH) and patients with either Cushing's disease or Ectopic ACTH Syndrome (EAS). Its drug candidates are orally delivered, small molecule new chemical entities resulting from in-house drug discovery efforts, including other programs addressing a variety of endocrine conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes and obesity.

AI analysis of Crinetics Pharmaceuticals Inc (CRNX)

hold

Crinetics Pharmaceuticals (CRNX) is currently trading at $84.84, very close to the analyst price target of $85. The RSI is at 82.058, indicating that the stock is overbought, which suggests caution for new buyers. The stock has shown a strong year-to-date change of +81.55% and a one-year change of +154.77%, reflecting significant growth. However, the forward P/E ratio is 0, indicating no earnings are expected in the near term, which is a risk for long-term investors. Given these factors, it's advisable to hold rather than buy at this moment, as the stock is near its acquisition price with limited upside potential.

Analyst Ratings (3)

+5.37% upside
Buy
2 Buy
1 Hold
0 Sell
Current: 84.84
Low
67.00
Average
89.40
High
105.00

UBS

2026-07-27

Price Target

$85

Neutral

Stifel

2026-07-08

Price Target

$85

Hold

Evercore ISI

2026-07-07

Price Target

$85

In Line

Jefferies

2026-07-07

Price Target

$85

Hold

JonesResearch

2026-07-07

Price Target

$85

Hold

Valuation Metrics

The current forward P/E ratio for Crinetics Pharmaceuticals Inc (CRNX) is 0.00, compared to its 5-year average forward P/E of -8.38.

Forward P/E

Strongly Overvalued
5Y Average P/E
-8.38
Current P/E
0.00
Overvalued
-5.43
Undervalued
-11.32

Forward EV/EBITDA

Undervalued
5Y Average EV/EBITDA
-5.25
Current EV/EBITDA
-9.49
Overvalued
-1.96
Undervalued
-8.53

Forward P/S

Fair
5Y Average P/S
944.15
Current P/S
49.89
Overvalued
2193.66
Undervalued
-305.35

Alphio AI Price Scenarios for CRNX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%CRNX

$35.84

Scenario price

B

Base

Base · 50%CRNX

$29.77

Scenario price

B

Bear

Bear · 25%CRNX

$27.24

Scenario price

Whales holding CRNX

B

Baker Bros. Advisors LP

+ HoldingCRNX

+18.95%

3M Return

B

Bellevue Asset Management AG

+ HoldingCRNX

+9.20%

3M Return

O

OrbiMed Advisors LLC

+ HoldingCRNX

+5.01%

3M Return

S

Suvretta Capital Management, LLC

+ HoldingCRNX

+2.26%

3M Return

A

ADAR1 Capital Management, LLC

+ HoldingCRNX

+2.25%

3M Return

A

Artal Group S.A.

+ HoldingCRNX

-0.61%

3M Return

Events Timeline

2026-08-03 (ET)

17:00:00

Company Reports Q2 Revenue of $25.12M

2026-07-07 (ET)

16:30:00

Nasdaq Retreats Amid Chip Sector Declines

16:30:00

TD Cowen Downgrades Crinetics to Hold

13:00:00

Citizens Analyst Downgrades Crinetics to Market Perform After $85 Acquisition by Vertex Pharmaceuticals

12:30:00

Crinetics Stock Rises 98.8% to $83.55

News

CRNX FAQ — answered by Alphio AI

Crinetics Pharmaceuticals, Inc. is a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of therapeutics for rare endocrine diseases and endocrine-related tumors. Its lead development candidate, PALSONIFY (paltusotine), is the first investigational once-daily, oral, selective somatostatin receptor type 2 (SST2) nonpeptide agonist that is in clinical development for acromegaly and carcinoid syndrome associated with neuroendocrine tumors. Its second product candidate is Atumelnant, which is in clinical development for congenital adrenal hyperplasia (CAH) and patients with either Cushing's disease or Ectopic ACTH Syndrome (EAS). Its drug candidates are orally delivered, small molecule new chemical entities resulting from in-house drug discovery efforts, including other programs addressing a variety of endocrine conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes and obesity. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Crinetics Pharmaceuticals (CRNX) is currently trading at $84.84, very close to the analyst price target of $85. The RSI is at 82.058, indicating that the stock is overbought, which suggests caution for new buyers. The stock has shown a strong year-to-date change of +81.55% and a one-year change of +154.77%, reflecting significant growth. However, the forward P/E ratio is 0, indicating no earnings are expected in the near term, which is a risk for long-term investors. Given these factors, it's advisable to hold rather than buy at this moment, as the stock is near its acquisition price with limited upside potential.

3 analysts cover CRNX: 2 rate it Buy, 1 Hold and 0 Sell. The average price target is 89.40.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

Get Started