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KAPA 資訊
KAPA 事件
Kairos Pharma Announces 1-for-7 Reverse Stock Split
Kairos Pharma announced that it will conduct a reverse stock split of its outstanding shares of common stock at a ratio of 1-for-7. The Reverse Stock Split is expected to become effective on September 1, 2026 at 12:01 a.m. ET, with shares expected to begin trading on the NYSE American on a split-adjusted basis at market open on September 1, 2026 under the existing trading symbol "KAPA" and a new CUSIP number of 48301N203. In connection with the Reverse Stock Split, every seven shares of the company's common stock issued and outstanding immediately prior to the Effective Time will be automatically reclassified and combined into one share of common stock. No fractional shares of common stock will be issued as a result of the Reverse Stock Split. Instead, the Company will issue to holders of record who were entitled to a fraction of a share as a result of the Reverse Stock Split, a fraction of a share of common stock as is necessary to round up to the nearest whole share. For shares held through The Depository Trust Company, fractions of shares will be issued as is necessary to round up to the nearest whole share at the DTC participant level. Brokers, banks or other nominees holding shares in "street name" will be instructed to effect the Reverse Stock Split for their beneficial holders; however, such brokers, banks or other nominees may apply their own specific procedures for processing the Reverse Stock Split.
Kairos Pharma Announces Strategic Collaboration with Bayer
Kairos Pharma (KAPA) announced a strategic collaboration with Bayer (BAYRY) to evaluate Kairos Pharma's lead antibody ENV-105, a first-in-class CD105/BMP signaling inhibitor, in combination with Bayer's XOFIGO in metastatic castration-resistant prostate cancer involving bone. "Drug resistance remains one of the greatest challenges in advanced prostate cancer, and XOFIGO, like many standard-of-care therapies, can lose efficacy over time," said John Yu, M.D., Kairos Pharma Chief Executive Officer. "ENV-105 has already demonstrated the ability to re-sensitize tumors to existing treatments with a strong safety profile, and this collaboration with Bayer represents a major milestone in our mission to deliver more durable and more effective treatment regimens for patients with metastatic prostate cancer."
Kairos Pharma Announces Interim Safety Data for ENV-105 Clinical Trial
Kairos Pharma announced interim safety data from its ongoing Phase 1 clinical trial evaluating ENV-105 in combination with osimertinib in patients with advanced EGFR-mutated non-small cell lung cancer, NSCLC. The data represent a milestone in Kairos Pharma's lead program: resensitizing patients who have acquired resistance to osimertinib, the global standard-of-care for EGFR-mutated NSCLC. With no serious adverse events observed across 13 treated patients to date from ENV-105 treatment, the safety profile supports continued progression toward an early efficacy readout.
Kairos Pharma Acquires Oncology Asset from Celyn Therapeutics
Kairos Pharma provides a mid-year update for 2026 and a look ahead to the rest of the year in a letter to shareholders from CEO John Yu, M.D.: "As we move toward the close of the second quarter, Kairos has been focused on adding some potentially impactful new development candidates to our existing pipeline. We announced the signing of a term sheet for a strategic asset acquisition with Celyn Therapeutics, Inc., a privately held biotechnology company backed by OrbiMed and Torrey Pines Investment. The Company will be acquiring the worldwide rights for a highly differentiated, clinical-stage oncology asset targeting non-small cell lung cancer and esophageal and gastric cancer: CL-741, a Phase 1-ready, orally available type IIb c-MET kinase inhibitor... CL-741 will add to our already existing portfolio of exciting targets, including ENV-105, KROS-201, KROS-102 and ENV-205. We remain committed to seeing these therapeutics through the clinical system alongside our partners utilizing non-dilutive clinical funding as much as possible."
Kairos Pharma Enters Binding Terms to Acquire CL-273
Kairos Pharma announces that it has entered into binding terms to acquire CL-273 from Celyn Therapeutics, a company backed by OrbiMed and Torrey Pines Investment. John Yu, M.D., Kairos Pharma CEO, commented: "The signing of binding terms to acquire CL-273 represents a pivotal step in building Kairos Pharma's next generation of targeted therapies for EGFR-mutant lung cancer. This transaction is expected to be value-accretive. CL-273's AI-designed, wild-type-sparing pan-EGFR profile positions it as a potentially best-in-class asset in a large, fast-growing $16.2 billion lung cancer market with significant unmet needs due to the development of resistance. Given its prestigious backing, we believe partnering with Celyn Therapeutics offers additional high-quality science to our existing pipeline. We believe in the rigor of the data package supporting CL-273. We further believe that together with an OrbiMed-backed innovator, Kairos Pharma is strongly positioned to deliver a highly differentiated, potentially best-in-class, EGFR inhibitor to patients worldwide."
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